Weight Loss May 27, 2026
RCT · Lancet (London, England)

New Daily Pill Shows Promise for Diabetes and Weight

A new phase 3 trial reveals that a daily oral pill called orforglipron could provide a highly effective, injection-free alternative for managing type 2 diabetes and body weight.

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Weight Loss May 27, 2026
RCT · Nature Medicine

New Drug Combo Accelerates Fat Loss While Protecting Muscle

A new clinical trial shows that pairing the antibody bimagrumab with semaglutide leads to dramatic fat loss while helping preserve critical muscle mass.

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Weight Loss May 20, 2026
Meta-analysis · JAMA internal medicine

Women Lose More Weight Than Men on GLP-1 Medications

A new analysis reveals that popular GLP-1 medications lead to significantly more percentage body mass reduction in women than in men.

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Weight Loss May 20, 2026
RCT · The Lancet

Popular GLP-1 Drug Fails to Slow Alzheimer's Disease Progression

Despite early promise, a large clinical trial reveals that the popular GLP-1 drug semaglutide does not slow down cognitive decline in early-stage Alzheimer's disease.

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Weight Loss May 6, 2026
Cohort study · Diabetes, obesity & metabolism

Semaglutide May Outperform Tirzepatide for Heart Health in Obesity

A new real-world study suggests semaglutide provides greater protection against major cardiovascular events than tirzepatide in overweight adults with prior heart disease.

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Weight Loss Apr 29, 2026
Meta-analysis · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Tirzepatide Lowers Heart Attack and Stroke Risks in Diabetes

A new analysis of real-world data reveals that the popular medication tirzepatide significantly lowers the risk of heart attacks, stroke, and early death in people with type 2 diabetes.

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Weight Loss Apr 29, 2026
Cohort study · The Lancet Psychiatry

Popular Diabetes Drugs May Protect Against Worsening Mental Health

New research suggests that medications like semaglutide could actually protect against worsening anxiety and depression rather than exacerbating them.

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Weight Loss Apr 22, 2026
Animal study · Cell metabolism

Semaglutide Protects Against Osteoarthritis Even Without Weight Loss

Semaglutide could relieve osteoarthritis pain and repair cartilage by changing how joint cells use energy, rather than just by shedding pounds.

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Weight Loss Apr 22, 2026
Other · Hepatology (Baltimore, Md.)

New Guidelines: How Semaglutide Treats Fatty Liver Disease

Liver experts have released new guidelines on using the popular drug semaglutide to treat a serious form of fatty liver disease.

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